Clinical Research & News

Read the latest research and articles about stem cell therapy and regenerative medicine.

Use of Mesenchymal Stem Cells in Treatment of Secondary Issues Related to Coronavirus

March 17, 2020 - Predictive Technology Group today announced that last week it began communication with domestic and international agencies and groups to be a supplier of mesenchymal stem cells (MSCs) for the potential clinical treatment of patients suffering from secondary issues related to the coronavirus (COVID-19).

stem cell treatment

Patient-derived stem cell therapy trial for geographic atrophy launches

December 17, 2019 - A clinical trial testing the safety of a patient-specific stem cell-based therapy for the treatment of geographic atrophy has been launched by the National Institutes of Health, according to a press release.

NIH launches first U.S. clinical trial of patient-derived stem cell therapy to replace dying cells in retina

December 16, 2019 - NEI-led study to test safety of treatment for a form of age-related macular degeneration that currently lacks treatment.

The life and fate of mesenchymal stem cells

Wharton’s jelly (WJ) is a gelatinous tissue within the umbilical cord that contains myofibroblast-like stromal cells. A unique cell population of WJ that has been suggested as displaying the stemness phenotype is the mesenchymal stromal cells (MSCs).

Concise Review: Wharton’s Jelly: The Rich, but Enigmatic, Source of Mesenchymal Stromal Cell

The umbilical cord has become an increasingly used source of mesenchymal stromal cells for preclinical and, more recently, clinical studies. Despite the increased activity, several aspects of this cell population have been under-appreciated. 

Umbilical Cord Tissue for Research and Clinical Application

Variations in allogeneic mesenchymal stem cell harvest levels from human tissues reflect the evolving nature of the field, patient demographic characteristics, and differences in harvest and isolation techniques. At present,Wharton’s jelly tissue yields the highest concentration of allogeneic mesenchymal stem cells. 

Effect of Aging on Stem Cells

Pluripotent stem cells have the remarkable self-renewal ability and are capable of differentiating into multiple diverse cells. There is increasing evidence that the aging process can have adverse effects on stem cells. As stem cells age, their renewal ability deteriorates and their ability to differentiate into the various cell types is altered. 

Consequences of Telomere Shortening During Lifespan

Telomerase expression is restricted in human cells and so telomeres shorten throughout our lives, providing a tumor suppressor mechanism that limits cell proliferation. As a trade-off, continuous telomere erosion results in replicative senescence and contributes to aging. 

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